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- Talk
- 14/07/2021
- UK
Biologics in Osteo Arthritis and Cartilage Repair
Description
The presentation, led by Daniel Saris, an orthopaedic sports medicine surgeon at the Mayo Clinic and the Utrecht Regenerative Medicine Center, focuses on innovative research and treatment strategies for cartilage repair in osteoarthritis utilizing biological methods. Saris opens by expressing gratitude for the opportunity to speak and emphasizes the collaborative efforts between American and European research groups that have advanced their clinical work. He discusses the ongoing challenges in the field, noting the evolving landscape of industry choices that can impact clinical practices. Saris presents a vision for the future where tissue recycling and the use of mesenchymal stem cells (MSCs) play pivotal roles in enhancing healing processes, ultimately aiming to restore patients to active lifestyles after joint damage.
He outlines the limitations of the human body in self-repair and posits that creativity and technology can bridge gaps in treatment capabilities. Saris emphasizes the importance of novel regenerative strategies, bridging disciplines and leveraging cells' intrinsic capabilities to improve healing outcomes. He reflects on the increasing prevalence of osteoarthritis and its societal burden, highlighting the need for effective treatments beyond traditional surgical interventions.
Saris also presents data regarding the efficacy and safety of various forms of injections—such as PRP and MSCs—emphasizing the necessity for controlled trials to understand their full impact. He discusses a technique that combines autologous tissue with allogeneic MSCs, presenting promising results from first-in-man studies in Europe and the United States, which suggest that such methods could effectively treat cartilage defects in a single surgical procedure.
Throughout the presentation, Saris interweaves a narrative of hope and scientific rigor, stressing the need for continuous advancements in regenerative medicine, while joyfully anticipating the contribution of ongoing research to alleviate the burden of joint diseases.