Description
The presented text is the transcript of a lecture given by Gino Kerkhoffs about emerging biological treatments for muscle injuries. It begins with an introduction where Kerkhoffs expresses gratitude to his hosts and outlines the absence of conflicts of interest. He then sets the stage for discussing the physiology of muscle healing, emphasizing the need for quicker recovery and fewer instances of re-injury.
Throughout the lecture, Kerkhoffs delves into various treatments available for muscle injuries, such as platelet-rich plasma (PRP) and other injection therapies like Actovegin and Traumeel. He discusses the physiological phases of muscle healing, from necrosis to regeneration and remodeling, and introduces the potential benefits of newer therapies while noting that some have limited or no clinical evidence supporting their efficacy.
Kerkhoffs mentions the possibility that the benefits of PRP might stem from a placebo effect, and discusses the complications associated with injection therapies, including potential harmful effects derived from steroids and local anesthetics. He concludes by advising caution regarding the use of these therapies, noting that while promising, many still lack substantial evidence in clinical practice. He urges that further controlled studies are needed for treatments such as antifibrotic agents and stem cells. The session ends with Kerkhoffs inviting further discussion on the topic, highlighting the complexities involved in treating muscle injuries.