Defining Phenotypes in Total Knee Arthroplasty Based on Intra-Operative Kinematics: A Multi-Center Cohort of 3915 Patients

Description

In this presentation, an R&D engineer introduces the concept of phenotypes in the context of patient classification for total knee arthroplasty (TKA) surgery. The speaker highlights the importance of categorizing patients to develop individualized surgical solutions and emphasizes the significance of coronal plane alignment parameters, such as HCCA, LGFA, and PTA. The discussion then shifts to the axial plane, focusing on anterior-posterior (AP) shift and knee kinematics during surgery. Data from 3,900 navigated cases were analyzed using an imageless navigation technique to determine knee kinematics at various flexion angles. The presentation details a proposed classification system based on AP shift direction and pivoting points, uncovering variability in knee behavior, particularly during flexion. Results indicate that a posterior shift is common, especially at 30 degrees of flexion, with different pivoting patterns categorized. The study concludes that understanding these variations aids in selecting appropriate TKA implant systems and suggests incorporating this classification into future surgical navigation software.

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