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- Talk
- 22/09/2022
- UK
Intra-Articular Injection and Knee Arthroscopy Prior to Primary Knee Replacement are Each Associated With Worse Outcomes. Analysis of Data From CPRD-HES-PROMs
Description
In this presentation, Matthew Strang discusses his research conducted during his master's program at the University of Bristol, focusing on the effects of corticosteroid injections and knee arthroscopy on the outcomes of knee replacements. He begins by highlighting the inconsistencies in the existing literature and the importance of exploring these interventions, given that about 30% of patients undergoing primary knee replacements have had either procedure. Strang presents a large observational study involving 38,494 patients and examines the impact of injections and arthroscopy on revision rates, reoperation rates, and other key outcomes such as infection rates and mortality.
The findings show that injections prior to knee replacements are associated with a higher risk of revision and a lower 15-year implant survival rate compared to those who did not receive injections. Conversely, knee arthroscopy is also linked to an increased risk of revision and poor clinical outcomes, though it does not correlate with increased infection rates. Strang discusses the implications of these results and emphasizes the necessity for surgeons to inform patients about the potential adverse effects of these interventions.
He acknowledges the strengths of the study, such as its size and robustness, while also noting inherent limitations due to its observational nature. The presentation concludes with recommendations for future research to uncover potential causal pathways behind these associations.